BDBM245898 US9428514, 86

SMILES CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)Cn2nc(C)cc2C)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=JSUSOOMWINJFNY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245898   

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandPNGBDBM245898(US9428514, 86)
Affinity DataKi:  22.6nM ΔG°:  -10.4kcal/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandPNGBDBM245898(US9428514, 86)
Affinity DataKi: >238nM ΔG°: >-9.03kcal/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent