BDBM246407 US9446130, 25

SMILES CC(C)Oc1ccnc(NC(=O)c2ccc(cc2)-c2nc(N3CCn4c(C3)nnc4C(F)(F)F)n3ccnc(N)c23)c1

InChI Key InChIKey=PBOGXWOJLHDIPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246407   

TargetTyrosine-protein kinase BTK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM246407(US9446130, 25)
Affinity DataIC50: 43nMAssay Description:Assay Method B: BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent