BDBM246642 US9550763, Compound I-290

SMILES Cc1cnc(-c2c[nH]/c(=N\c3ccc(Oc4cccc(C(=O)O)n4)cc3)n(Cc3ccc(Cl)cc3)c2=O)o1

InChI Key InChIKey=VUGVNVZKDFCRLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246642   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 246642BDBM246642(US9550763, Compound I-290)
Affinity DataIC50: 4nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent