BDBM246655 US9550763, Compound I-308

SMILES Cc1ccc(Oc2ccc(/N=c3\[nH]cc(NC(=O)[C@H]4C[C@H](O)C4)c(=O)n3Cc3ccc(Cl)cc3)cc2)nn1

InChI Key InChIKey=CQAURIGAGAANEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246655   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 246655BDBM246655(US9550763, Compound I-308)
Affinity DataIC50: 5nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent