BDBM246778 US9550763, Compound I-435

SMILES O=C(Nc1c[nH]/c(=N\c2ccc(Oc3ccc(C(F)(F)F)nn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C1CCOCC1

InChI Key InChIKey=RBWPIUBNPISUFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246778   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 246778BDBM246778(US9550763, Compound I-435)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent