BDBM246778 US9550763, Compound I-435

SMILES FC(F)(F)c1ccc(Oc2ccc(cc2)\N=c2/[nH]cc(NC(=O)C3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)nn1

InChI Key InChIKey=RBWPIUBNPISUFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246778   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM246778(US9550763, Compound I-435)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent