BDBM247316 US9447090, 766

SMILES Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)N[C@@]1(C[C@H](O)[C@H](O)C1)c1ccccc1

InChI Key InChIKey=HGEDIADWGUWLQH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247316   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Astellas Pharma

US Patent
LigandPNGBDBM247316(US9447090, 766)
Affinity DataEC50:  1.70E+4nMT: 2°CAssay Description:The activity of sGC was evaluated by measuring the amount of a cyclic guanosine monophosphate (cGMP) which is produced by human purified sGC. A test ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent