BDBM24769 5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinolin-4-yl}oxy)phenyl]-2-[(4-fluorophenyl)amino]-3-methyl-3,4-dihydropyrimidin-4-one::pyrimidone, 51
SMILES COc1cc2c(Oc3ccc(cc3F)-c3cnc(Nc4ccc(F)cc4)n(C)c3=O)ccnc2cc1OCCCN1CCOCC1
InChI Key InChIKey=ONSZEUCTVQJHOZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 24769
Affinity DataKi: 4.90nM ΔG°: -11.2kcal/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataKi: 139nM ΔG°: -9.25kcal/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair