BDBM247990 US9434724, 46
SMILES Oc1cc(Cl)c2c(c[nH]c2c1)C(=O)OCC12CCN(CC1)CC2
InChI Key InChIKey=ZZNMCYCBKMJHPV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 247990
Affinity DataKi: 28.6nM ΔG°: -10.7kcal/mole IC50: 33.4nMpH: 7.4 T: 2°CAssay Description:Protocol 1: The assay was conducted following the literature reference Meyer E. M., et al., Analysis of 3-(4-Hydroxy, 2-Methoxybenzylidene) Anabasein...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Alpharmagen
US Patent
Alpharmagen
US Patent
Affinity DataIC50: >3.00E+4nMpH: 7.4Assay Description:hERG study was conducted with an automated patch clamp machine, Qpatch-48HT (Sophion Biosciences, Denmark). Cultured CHO cells stably expressing hERG...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair