BDBM248052 5-(4-((5-phenylpyridin-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6c)

SMILES O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2cncc(c2)-c2ccccc2)CC1

InChI Key InChIKey=GHCLCIMAOYUDPI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 248052   

Target5-hydroxytryptamine receptor 1A(Human)
King Fahd University of Petroleum & Minerals

LigandPNGBDBM248052(5-(4-((5-phenylpyridin-3-yl)methyl)piperazin-1-yl)...)
Affinity DataKi:  5.30nM ΔG°:  -11.7kcal/molepH: 7.4 T: 2°CAssay Description:Human-cloned 5-HT1A serotonin receptors stably expressed in HEK293-EBNA cells (Perkin-Elmer, Waltham, MA) were radiolabeled with 1.0nM [3H]-8-OH-DPAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
King Fahd University of Petroleum & Minerals

LigandPNGBDBM248052(5-(4-((5-phenylpyridin-3-yl)methyl)piperazin-1-yl)...)
Affinity DataKi:  12.6nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:Human-cloned dopamine D2L receptors stably expressed in C6 rat glioma cells (kindly donated by Professor Roberto Maggio, Università di L'Aquil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed