BDBM248055 5-(4-((5-cyclopentenylpyridin-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6f)

SMILES O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2cncc(c2)C2=CCCC2)CC1

InChI Key InChIKey=CTRJCSXYHYSJGC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 248055   

Target5-hydroxytryptamine receptor 1A(Human)
King Fahd University of Petroleum & Minerals

LigandPNGBDBM248055(5-(4-((5-cyclopentenylpyridin-3-yl)methyl)piperazi...)
Affinity DataKi:  1.70nM ΔG°:  -12.4kcal/molepH: 7.4 T: 2°CAssay Description:Human-cloned 5-HT1A serotonin receptors stably expressed in HEK293-EBNA cells (Perkin-Elmer, Waltham, MA) were radiolabeled with 1.0nM [3H]-8-OH-DPAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
King Fahd University of Petroleum & Minerals

LigandPNGBDBM248055(5-(4-((5-cyclopentenylpyridin-3-yl)methyl)piperazi...)
Affinity DataKi:  3.10nM ΔG°:  -11.6kcal/molepH: 7.4 T: 2°CAssay Description:Human-cloned dopamine D2L receptors stably expressed in C6 rat glioma cells (kindly donated by Professor Roberto Maggio, Università di L'Aquil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed