BDBM249384 US9464081, 17

SMILES [#7]-[#6](=O)-c1nn(-[#6]-[#6](=O)-[#7]-2-[#6@@H]-3-[#6]-[#6@@H]-3-[#6]-[#6@H]-2-[#6](=O)-[#7]-[#6]\[#6](F)=[#6]-2\[#6]-[#6]-[#6]-[#6]-2)c2ccccc12

InChI Key InChIKey=COPRZRPSBTWUMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249384   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM249384(US9464081, 17)
Affinity DataIC50: 128nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent