BDBM2498 (+/-)-4-Hydroxy-3-[4-methyl-l-(phenylthio)pentyl]-phenyl-2H-pyran-2-one::4-hydroxy-3-[4-methyl-1-(phenylsulfanyl)pentyl]-6-phenyl-2H-pyran-2-one::C-3-substituted Pyran-2-one 7

SMILES CC(C)CCC(Sc1ccccc1)c1c(O)cc(oc1=O)-c1ccccc1

InChI Key InChIKey=OJWIIEFLUZBLJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2498   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2498(4-hydroxy-3-[4-methyl-1-(phenylsulfanyl)pentyl]-6-...)
Affinity DataIC50: 390nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2004
Entry Details Article
PubMed