BDBM249971 US10005782, Compound 97::US9447106, 97::US9556188, Compound 97

SMILES NC(=O)c1c2NCCC(c3ccc(Cl)c(NC(=O)C=C)c3)n2nc1-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=BWOVWJAFPITQNY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 249971   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249971(US9447106, 97 | US9556188, Compound 97 | US1000578...)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249971(US9447106, 97 | US9556188, Compound 97 | US1000578...)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249971(US9447106, 97 | US9556188, Compound 97 | US1000578...)
Affinity DataIC50: 1.10nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent