BDBM250083 US9447106, 29a (peak 1)::US9556188, Compound 29b

SMILES NC(=O)c1c2NCC[C@H](C3CN(C3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=PKGJEJSOPQZJNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 250083   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM250083(US9447106, 29a (peak 1) | US9556188, Compound 29b)
Affinity DataIC50: 0.430nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM250083(US9447106, 29a (peak 1) | US9556188, Compound 29b)
Affinity DataIC50: 1.30nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent