BDBM250086 US10005782, Compound 30b::US9447106, 30b (peak 2)

SMILES NC(=O)c1c2NC[C@H]3CN(CC[C@@H]3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C

InChI Key InChIKey=STKAJAXFRAFMLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 250086   

TargetTyrosine-protein kinase BTK(Human)
Beigene Switzerland

US Patent
LigandPNGBDBM250086(US9447106, 30b (peak 2) | US10005782, Compound 30b...)
Affinity DataIC50: 0.660nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene Switzerland

US Patent
LigandPNGBDBM250086(US9447106, 30b (peak 2) | US10005782, Compound 30b...)
Affinity DataIC50: 16nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene Switzerland

US Patent
LigandPNGBDBM250086(US9447106, 30b (peak 2) | US10005782, Compound 30b...)
Affinity DataIC50: 16nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent