BDBM2506 (+/-)-3-[1-(Cyclohexylthio)-2-cyclopentylethyl]-4-hydroxy-6-phenyl-2H-pyran-2-one::3-[1-(cyclohexylsulfanyl)-2-cyclopentylethyl]-4-hydroxy-6-phenyl-2H-pyran-2-one::C-3-substituted Pyran-2-one 15

SMILES Oc1cc(oc(=O)c1C(CC1CCCC1)SC1CCCCC1)-c1ccccc1

InChI Key InChIKey=PYRLSOHLBKBNQV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2506   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2506(3-[1-(cyclohexylsulfanyl)-2-cyclopentylethyl]-4-hy...)
Affinity DataIC50: 541nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2004
Entry Details Article
PubMed