BDBM252435 US9458172, 2

SMILES Fc1cc(F)cc(c1)S(=O)(=O)c1ccc(CNC(=O)c2cnc3nccn3c2)nc1

InChI Key InChIKey=IBYUQAZWTCJJFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 252435   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM252435(US9458172, 2)
Affinity DataIC50: 6.5nMpH: 7.5Assay Description:The NAMPT Enzymatic Reaction. The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent