BDBM252644 US9458176, 41

SMILES COc1cc(ccc1C(F)(F)F)-c1nc(c2CCO[C@H](CF)Cn12)-c1ccnc(C)c1

InChI Key InChIKey=IMEPFIQPXFUSMQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 252644   

TargetMetabotropic glutamate receptor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM252644(US9458176, 41)
Affinity DataIC50: 4.10nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent