BDBM25390 7-benzyl-3-methyl-8-[(2Z)-2-(1-phenylethylidene)hydrazin-1-yl]-2,3,6,7-tetrahydro-1H-purine-2,6-dione::purine-2,6-dione, 33

SMILES CC(N=Nc1nc2n(C)c(=O)[nH]c(=O)c2n1Cc1ccccc1)c1ccccc1

InChI Key InChIKey=IZILBHQYAZKAKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25390   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Pennsylvania

LigandPNGBDBM25390(7-benzyl-3-methyl-8-[(2Z)-2-(1-phenylethylidene)hy...)
Affinity DataIC50: 1.14E+4nMpH: 7.0 T: 2°CAssay Description:BRAF kinase activity was quantified using an ELISA-based MEK phosphorylation assay. IC50 values were derived from the sigmoidal dose-response curve f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed