BDBM254077 US9493474, 9

SMILES O[C@@H](CN1CC2CCN(C2C1)S(=O)(=O)c1ccc(cc1)[N+]#[C-])c1ccc2C(=O)OCc2c1

InChI Key InChIKey=KODXHNMDXQPYNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254077   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM254077(US9493474, 9)
Affinity DataIC50: 234nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent