BDBM254463 US9468661, 41

SMILES CO[C@@H]1[C@@H](F)CN([C@@H]1C(=O)NC[C@H]1CC1(Cl)Cl)C(=O)Cn1nc(C(N)=O)c2ccc(Cl)cc12

InChI Key InChIKey=SOOOXNKSJQVBSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254463   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM254463(US9468661, 41)
Affinity DataIC50: 51nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent