BDBM255999 US9481672, 177

SMILES CN1c2ccc(cc2N(C)S1(=O)=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2C)C(F)(F)F)c1=O

InChI Key InChIKey=WENXSFWULKEAGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 255999   

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255999BDBM255999(US9481672, 177)
Affinity DataIC50: 30nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

TargetChymase(Human)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 255999BDBM255999(US9481672, 177)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetChymase(Canis lupus familiaris)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 255999BDBM255999(US9481672, 177)
Affinity DataIC50: 170nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed