BDBM256070 BDBM256071::BDBM256072::US9481672, 252

SMILES CC(c1cccc(c1C)C(F)(F)F)n1c(=O)c(cn(-c2ccc3n(C)c(=O)n(C)c3c2)c1=O)C(O)=O

InChI Key InChIKey=KIBBJCSNNIOINZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 256070   

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256070BDBM256070(US9481672, 252 | BDBM256071 | BDBM256072)
Affinity DataIC50: 84nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256070BDBM256070(US9481672, 252 | BDBM256071 | BDBM256072)
Affinity DataIC50: 190nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

TargetChymase(Canis lupus familiaris)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 256070BDBM256070(US9481672, 252 | BDBM256071 | BDBM256072)
Affinity DataIC50: 260nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetChymase(Human)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 256070BDBM256070(US9481672, 252 | BDBM256071 | BDBM256072)
Affinity DataIC50: 610nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256070BDBM256070(US9481672, 252 | BDBM256071 | BDBM256072)
Affinity DataIC50: 1.50E+3nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

TargetChymase(Canis lupus familiaris)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 256070BDBM256070(US9481672, 252 | BDBM256071 | BDBM256072)
Affinity DataIC50: 8.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetChymase(Human)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 256070BDBM256070(US9481672, 252 | BDBM256071 | BDBM256072)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed