BDBM256277 US9487488, 1

SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)cc1

InChI Key InChIKey=HLLKNPAVDRASLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 256277   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM256277(US9487488, 1)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM256277(US9487488, 1)
Affinity DataIC50: 0.300nMT: 2°CAssay Description:The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent