BDBM25655 6-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-1H-indazole::pyrazole based inhibitor, 37

SMILES Cn1cc(c(n1)-c1ccncc1)-c1ccc2cn[nH]c2c1

InChI Key InChIKey=RGCICAWWIIRITL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25655   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

LigandPNGBDBM25655(6-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-1H-i...)
Affinity DataIC50: 70nMAssay Description:Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

LigandPNGBDBM25655(6-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-1H-i...)
Affinity DataIC50: 139nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed