BDBM25667 5-bromo-N-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine::aminothiazole analogue, 11

SMILES FC(F)(F)c1ccc(Nc2ncc(Br)s2)cc1

InChI Key InChIKey=DUZSVOIDXYBLLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25667   

TargetAurora kinase A(Human)
Novartis

LigandPNGBDBM25667(5-bromo-N-[4-(trifluoromethyl)phenyl]-1,3-thiazol-...)
Affinity DataIC50: 2.40E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
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Date in BDB:
11/24/2008
Entry Details Article
PubMed