BDBM25705 5-bromo-N-(2,5-difluorophenyl)-1,3-thiazol-2-amine::aminothiazole analogue, 49

SMILES Fc1ccc(F)c(Nc2ncc(Br)s2)c1

InChI Key InChIKey=XEAPRJHGSXBYOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25705   

TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25705BDBM25705(5-bromo-N-(2,5-difluorophenyl)-1,3-thiazol-2-amine...)
Affinity DataIC50: 1.00E+4nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed