BDBM25709 N-[3,5-bis(trifluoromethyl)phenyl]-5-bromo-1,3-thiazol-2-amine::aminothiazole analogue, 53

SMILES FC(F)(F)c1cc(Nc2ncc(Br)s2)cc(c1)C(F)(F)F

InChI Key InChIKey=AKROENBNDUQJEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25709   

TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25709BDBM25709(N-[3,5-bis(trifluoromethyl)phenyl]-5-bromo-1,3-thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed