BDBM258374 US9505786, 12

SMILES Cc1cccc(Cn2nc(-c3nnc4c(NC(=O)C4(C)C)n3)c3cc(F)cnc23)c1F

InChI Key InChIKey=XWTRMTNXCPMRGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258374   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM258374(US9505786, 12)
Affinity DataIC50: 580nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent