BDBM258533 US10633384, Example 7.1::US9493486, 7.1

SMILES O=C(c1ccc2[nH]nnc2c1)N1CC2(CCN(c3nnc(-c4ccc(Cl)cc4)o3)CC2)C1

InChI Key InChIKey=UEEMHDQTRLSWSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 258533   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 258533BDBM258533(US9493486, 7.1 | US10633384, Example 7.1)
Affinity DataIC50: 260nMpH: 8.0 T: 2°CAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 258533BDBM258533(US9493486, 7.1 | US10633384, Example 7.1)
Affinity DataIC50: 260nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2021
Entry Details
US Patent