BDBM259084 US9499502, 22f
SMILES CC1=NOC(CNC(=O)c2cc(Cl)c(s2)[C@]2(C)CS(=O)(=O)C(C)(C)C(=N)N2)C1
InChI Key InChIKey=VMSRYVFUGKAOSD-LKDXBUKQSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 259084
Affinity DataKi: 616nM ΔG°: -8.61kcal/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nM ΔG°: -7.96kcal/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair