BDBM2592 (Arylindolyl)maleimide deriv. 14::3-(1-benzyl-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(Cc3ccccc3)c3ccccc23)c2ccccc12

InChI Key InChIKey=HSFXDRBLOFSTNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2592   

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2592(3-(1-benzyl-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-...)
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM2592(3-(1-benzyl-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-...)
Affinity DataIC50: 1.00E+5nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed