BDBM25923 12-methyl-N-[2-(piperidin-1-yl)ethyl]-11,14,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,12,14,16-octaen-16-amine::benzimidazoquinoxaline analogue, 7d

SMILES Cc1cnc2c(NCCN3CCCCC3)nc3cc4ccccc4cc3n12

InChI Key InChIKey=KFIFSKNSIUVOCG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25923   

LigandPNGBDBM25923(12-methyl-N-[2-(piperidin-1-yl)ethyl]-11,14,17-tri...)
Affinity DataIC50: 46nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2008
Entry Details Article
PubMed
LigandPNGBDBM25923(12-methyl-N-[2-(piperidin-1-yl)ethyl]-11,14,17-tri...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM25923(12-methyl-N-[2-(piperidin-1-yl)ethyl]-11,14,17-tri...)
Affinity DataIC50: 1.70E+3nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2008
Entry Details Article
PubMed