BDBM25926 N-(2-aminoethyl)-12-methyl-12,14,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,11(15),13,16-octaen-16-amine::benzimidazoquinoline analogue, 18b

SMILES Cn1cnc2c(NCCN)nc3cc4ccccc4cc3c12

InChI Key InChIKey=AKFPEKVULJCIRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25926   

LigandPNGBDBM25926(N-(2-aminoethyl)-12-methyl-12,14,17-triazatetracyc...)
Affinity DataIC50: 58nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2008
Entry Details Article
PubMed
LigandPNGBDBM25926(N-(2-aminoethyl)-12-methyl-12,14,17-triazatetracyc...)
Affinity DataIC50: 1.60E+3nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2008
Entry Details Article
PubMed