BDBM25927 benzopyrazoloquinazoline analogue, 13b::methyl[2-({12-methyl-14,15,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,11,13,16-octaen-16-yl}amino)ethyl]amine

SMILES CNCCNc1nc2cc3ccccc3cc2c2c(C)cnn12

InChI Key InChIKey=MZGNCCPVHUSMIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25927   

LigandPNGBDBM25927(methyl[2-({12-methyl-14,15,17-triazatetracyclo[8.7...)
Affinity DataIC50: 35nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2008
Entry Details Article
PubMed
LigandPNGBDBM25927(methyl[2-({12-methyl-14,15,17-triazatetracyclo[8.7...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed