BDBM259344 US9505745, 21

SMILES Cc1cc(C)c(CNC(=O)c2csc(C(O)C3CCNCC3)c2C)c(=O)[nH]1

InChI Key InChIKey=YGPOYOZOXJDGSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259344   

LigandChemical structure of BindingDB Monomer ID 259344BDBM259344(US9505745, 21)
Affinity DataIC50: 100nMAssay Description:Protocol 1: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 259344BDBM259344(US9505745, 21)
Affinity DataIC50: 316nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent