BDBM25935 N-(2-aminoethyl)-12-methyl-4-(pyridin-2-yl)-3-thia-1,7,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),4,7,9,11-pentaen-8-amine::imidazothienopyrazine, 13h

SMILES Cc1cnc2c(NCCN)nc3cc(sc3n12)-c1ccccn1

InChI Key InChIKey=ZHGOPVNOSIOFRT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25935   

LigandPNGBDBM25935(N-(2-aminoethyl)-12-methyl-4-(pyridin-2-yl)-3-thia...)
Affinity DataIC50: 190nMAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed
LigandPNGBDBM25935(N-(2-aminoethyl)-12-methyl-4-(pyridin-2-yl)-3-thia...)
Affinity DataIC50: 191nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM25935(N-(2-aminoethyl)-12-methyl-4-(pyridin-2-yl)-3-thia...)
Affinity DataIC50: 1.24E+3nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed