BDBM259361 US9505745, 38::US9790212, Example 38

SMILES Cc1cc(C)c(CNC(=O)c2csc(C(O)[C@H]3CC[C@H](N(C)C)CC3)c2C)c(=O)[nH]1

InChI Key InChIKey=LLXDKFMURVBHJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259361   

LigandChemical structure of BindingDB Monomer ID 259361BDBM259361(US9505745, 38 | US9790212, Example 38)
Affinity DataIC50: 158nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 259361BDBM259361(US9505745, 38 | US9790212, Example 38)
Affinity DataIC50: 158nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent