BDBM259365 US9505745, 42::US9790212, Example 42

SMILES CC[C@H](c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)N1CCC(N(C)C)CC1

InChI Key InChIKey=LVGCTQDARMZPSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259365   

LigandChemical structure of BindingDB Monomer ID 259365BDBM259365(US9505745, 42 | US9790212, Example 42)
Affinity DataIC50: 316nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 259365BDBM259365(US9505745, 42 | US9790212, Example 42)
Affinity DataIC50: 316nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent