BDBM25941 (2-{8-[(2-aminoethyl)amino]-12-methyl-3-thia-1,7,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),4,7,9,11-pentaen-4-yl}phenyl)methanol::imidazothienopyrazine, 14d

SMILES Cc1cnc2c(NCCN)nc3cc(sc3n12)-c1ccccc1CO

InChI Key InChIKey=XGFBARHKTYXMCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25941   

LigandPNGBDBM25941((2-{8-[(2-aminoethyl)amino]-12-methyl-3-thia-1,7,1...)
Affinity DataIC50: 130nMAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed
LigandPNGBDBM25941((2-{8-[(2-aminoethyl)amino]-12-methyl-3-thia-1,7,1...)
Affinity DataIC50: 4.40E+3nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed