BDBM25949 dimethyl[2-({12-methyl-4-phenyl-3-thia-1,7,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),4,7,9,11-pentaen-8-yl}amino)ethyl]amine::imidazothienopyrazine, 20d

SMILES CN(C)CCNc1nc2cc(sc2n2c(C)cnc12)-c1ccccc1

InChI Key InChIKey=YEGWKIFISRCWRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25949   

LigandPNGBDBM25949(dimethyl[2-({12-methyl-4-phenyl-3-thia-1,7,10-tria...)
Affinity DataIC50: 95nMAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed
LigandPNGBDBM25949(dimethyl[2-({12-methyl-4-phenyl-3-thia-1,7,10-tria...)
Affinity DataIC50: 1.17E+3nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed