BDBM25976 2-amino-N-methyl-3-{3-[12-methyl-8-(methylamino)-3-thia-1,7,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),4,7,9,11-pentaen-4-yl]phenyl}propanamide::imidazothienopyrazine, 22t

SMILES CNC(=O)C(N)Cc1cccc(c1)-c1cc2nc(NC)c3ncc(C)n3c2s1

InChI Key InChIKey=MXCVCAHPICGSHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25976   

LigandPNGBDBM25976(2-amino-N-methyl-3-{3-[12-methyl-8-(methylamino)-3...)
Affinity DataIC50: 36nMAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed
LigandPNGBDBM25976(2-amino-N-methyl-3-{3-[12-methyl-8-(methylamino)-3...)
Affinity DataIC50: 330nMAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed