BDBM259902 US9512115, 5

SMILES CC(F)(F)COc1ccc(cc1F)[C@H]1COC(=O)N1c1ccc2[nH]cnc2c1

InChI Key InChIKey=IQQIFBUARJSBEK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259902   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM259902(US9512115, 5)
Affinity DataKi:  19.2nM ΔG°:  -10.7kcal/molepH: 8.0 T: 2°CAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM259902(US9512115, 5)
Affinity DataKi:  21.3nM ΔG°:  -10.6kcal/molepH: 6.0 T: 2°CAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
US Patent