BDBM260397 US9527838, 25

SMILES Cn1cnnc1Sc1ccc(Sc2ccc(F)cc2)c(n1)C(=O)Nc1nc(CC(O)=O)c(Cl)s1

InChI Key InChIKey=QETRVNKELLBAQW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260397   

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM260397(US9527838, 25)
Affinity DataEC50:  18.6nMAssay Description:Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E. coli, and purified on ANTIFLAG M2 AFFINITY GEL (Sigma). The assay wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent