BDBM260669 US9533985, 57

SMILES Cn1c2cnccc2c(=O)n(-c2ccc(C[C@H](NC(=O)c3c(F)cc(NS(=O)(=O)c4ccc(cn4)-n4cncn4)cc3F)C(O)=O)cc2)c1=O

InChI Key InChIKey=BDQBXEUFIFTAHI-DEOSSOPVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 260669   

LigandPNGBDBM260669(US9533985, 57)
Affinity DataIC50:  0.0600nMpH: 9.6 T: 4°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM260669(US9533985, 57)
Affinity DataIC50:  1.5nMpH: 9.6 T: 4°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM260669(US9533985, 57)
Affinity DataIC50:  13nMpH: 9.6 T: 4°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent