BDBM26077 2-(carbamoylamino)-5-[2-(thiophen-3-yl)ethynyl]thiophene-3-carboxamide::5-acetylenyl-3-thiophenecarboxamide, 1a

SMILES NC(=O)Nc1sc(cc1C(N)=O)C#Cc1ccsc1

InChI Key InChIKey=UURPHNQEUBECEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26077   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM26077(2-(carbamoylamino)-5-[2-(thiophen-3-yl)ethynyl]thi...)
Affinity DataIC50: 417nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM26077(2-(carbamoylamino)-5-[2-(thiophen-3-yl)ethynyl]thi...)
Affinity DataIC50: 420nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed