BDBM261139 3-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]pyrimidin-1- yl)ethyl]-5-chloro-2-methoxy-6- methylphenyl}azetidin-1-yl)-2- methylpropanenitrile4::US9707233, 162

SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(C)CC#N)C(C)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=YIRWZXGDZHMMSZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261139   

LigandPNGBDBM261139(3-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...)
Affinity DataIC50: 10nMpH: 6.7 T: 2°CAssay Description:Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent