BDBM261327 2-(4-((1r,4r)-4-amino-1-((4-fluorophenyl)sulfonyl)cyclohexyl)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::US9708253, 1

SMILES [#8]\[#7]=[#6]-1/[#6]-[#6]C([#6]-[#6]-1)(c1ccc(cc1)C([#8]-[#6]-c1ccccc1)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=DHBSJTJMKHPKKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261327   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM261327(2-(4-((1r,4r)-4-amino-1-((4-fluorophenyl)sulfonyl)...)
Affinity DataIC50: 80nMT: 2°CAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent