BDBM26143 Alkenylboronic Acid, 22::[(E)-2-(4-phenylphenyl)ethenyl]boranediol

SMILES OB(O)\C=C\c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NTRGFVQIGQYKIL-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26143   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Oxford

LigandPNGBDBM26143([(E)-2-(4-phenylphenyl)ethenyl]boranediol | Alkeny...)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM26143([(E)-2-(4-phenylphenyl)ethenyl]boranediol | Alkeny...)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Oxford

LigandPNGBDBM26143([(E)-2-(4-phenylphenyl)ethenyl]boranediol | Alkeny...)
Affinity DataIC50: 3.10E+4nMAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM26143([(E)-2-(4-phenylphenyl)ethenyl]boranediol | Alkeny...)
Affinity DataKi:  4.23E+4nMAssay Description:Inhibition of Candida albicans recombinant Carbonic anhydrase pre-incubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM26143([(E)-2-(4-phenylphenyl)ethenyl]boranediol | Alkeny...)
Affinity DataKi:  3.73E+5nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed