BDBM261453 4-((1s,4s)-4-(4-fluorophenylsulfonyl)-4-(4-(perfluoropropan-2-yl)phenyl)cyclohexyl)morpholine::US9708253, 112

SMILES Fc1ccc(cc1)S(=O)(=O)[C@@]1(CC[C@@H](CC1)N1CCOCC1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=PLZOJHICCQXZQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261453   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM261453(4-((1s,4s)-4-(4-fluorophenylsulfonyl)-4-(4-(perflu...)
Affinity DataIC50: 64nMT: 2°CAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent